Tetrahedron p. 7159 - 7164 (1997)
Update date:2022-08-05
Topics:
Diwu, Zhenjun
Lu, Yixin
Upson, Rosalyn H.
Zhou, Mingjie
Klaubert, Dieter H.
Haugland, Richard P.
A novel quinazolinone-based fluorogenic β-glucuronidase substrate has been synthesized and evaluated. In this protocol, a partially protected salicyl glucuronide is oxidatively condensed with anthranilamide to afford the required quinazolinonyl glucuronic acid methyl ester that is readily deprotected to yield the desired glucuronide, known as ELF-97 glucuronide. The glucuronide is a sensitive fluorogenic β-glucuronidase substrate that yields a bright yellow-green fluorescent precipitate upon enzymatic reaction.
View MoreShijiazhuang Haotian Chemical Co., Ltd.
Contact:86-311-85044374
Address:293 Donggang Road
SHAANXI TOP PHARM CHEMICAL CO.LTD
Contact:+86-029-85733403
Address:No.108 ,west sector,south er huan,xi'an,china
Jiangxi Hessence Chemicals Co., Ltd.
Contact:+86 796 3511924
Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Anhui Dexinjia Biopharm Co., Ltd
Contact:+86-531-82375818
Address:9 Hexie Road, kaifaqu, Taihe
Arshine Pharmaceutical Co., Limited
website:http://www.cnarshine.com
Contact:0731-88503671
Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China
Doi:10.1021/jm00312a029
(1968)Doi:10.1016/S0039-128X(99)00109-9
(2000)Doi:10.1021/jo970585o
(1997)Doi:10.1021/jo01258a058
(1969)Doi:10.1002/hlca.19750580842
(1975)Doi:10.1134/S1070427212080162
(2012)