Journal of Organic Chemistry p. 1363 - 1371 (2019)
Update date:2022-09-26
Topics:
Feskov, Illia O.
Chernykh, Anton V.
Kuchkovska, Yuliya O.
Daniliuc, Constantin G.
Kondratov, Ivan S.
Grygorenko, Oleksandr O.
Four 3-((hetera)cyclobutyl)azetidine-based isosteres of piperidine, piperazine, and morpholine were designed and synthesized on up to gram scale. The key step of the synthetic sequence included cyclization of N-protected 2-(azetidin-3-yl)propane-1,3-diol
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