Canadian Journal of Chemistry p. 1322 - 1330 (1997)
Update date:2022-08-04
Topics:
Kayser, Margaret M.
Zhu, Jun
Hooper, Donald L.
The synthesis of halo enol lactones from cyclic anhydrides via lactonization of the corresponding keto phosphoranes provides a direct route to these interesting compounds, which possess important biological properties and are useful intermediates in organic synthesis. In this paper we outline the syntheses of several halo enol lactones and discuss mechanistic consequences of these reactions on the understanding of Wittig reactions with cyclic anhydrides.
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