Bioorganic and Medicinal Chemistry Letters p. 1953 - 1956 (1999)
Update date:2022-08-04
Topics:
Anderson, Benjamin A.
Harn, Nancy K.
Hansen, Marvin M.
Harkness, Allen R.
Lodge, David
Leander, J. David
A novel series of 3-aryl-5H-2,3-benzodiazepines with N-3 aromatic substituents has been synthesized. Good in vivo anticonvulsant activity of the new compounds has been demonstrated employing the maximal electroshock seizure test in mice. Evaluation of a subset of the compounds in the cortical wedge assay confirmed the new structures to be AMPA antagonists.
View MoreShanghai HengXun Pharmaceutical Tech. Co., Ltd.
Contact:86-86-52730756
Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China
Daicel Chiral Technologies (China)CO.,LTD
Contact:021-5046-0086*8
Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Liaoyang Xinyou Chemical Products Co.,Ltd.
Contact:+86-419-5165433 13604191870
Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China
Chengdu NoVi Biotechnology Co., Ltd.
Contact:13551243286/028-81458053
Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Xuzhou Tianrun Chemical Co.,Ltd
website:http://www.tianrunchem.cn
Contact:86-516-83832636
Address:fuxing road
Doi:10.1016/j.cclet.2015.08.001
(2015)Doi:10.1002/hlca.19980810550
(1998)Doi:10.1134/S0036023610070090
(2010)Doi:10.1007/BF02495562
(1998)Doi:10.1021/acs.organomet.7b00469
(2017)Doi:10.1002/hlca.19710540140
(1971)