Heterocycles p. 189 - 198 (2003)
Update date:2022-08-02
Topics:
Burger, Klaus
Lange, Torsten
Rudolph, Martin
A highly efficient method for regiospecific α-functionalization of aspartic acid is described. Key step is the synthesis of a N-protected and regioselectively α-carboxy-activated heterocyclic intermediate from aspartic acid and hexafluoroacetone. The new strategy offers i.a. a two step access to the sweetener Aspartame and to libraries of aspartame analogues.
View MoreJiangxi Lixin Pharmaceutical Co.,Ltd.
Contact:0798-8337222; 18979813215
Address:Jiangxi City, Jindezheng Province
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.
Contact:+86-(574)-81110986
Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
website:http://www.apeptides.com/en/
Contact:+86-21-60871011
Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai
Chengdu Baishixing Science and Technology Industry Co., Ltd.
website:http://www.cd-bsx.com
Contact:+86-28-88531548
Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Shanghai Sinofluoro Scientific Co., Ltd
Contact:+86-21-64279360
Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Doi:10.1016/S0040-4039(01)92421-9
(1981)Doi:10.3987/COM-03-S(P)48
(2004)Doi:10.1002/mrc.1270130512
(1980)Doi:10.1007/BF00922874
()Doi:10.1016/S0040-4039(00)80155-0
(1988)Doi:10.1039/c7gc00192d
(2017)