Tetrahedron p. 11027 - 11038 (1999)
Update date:2022-08-03
Topics:
Alonso, Emma
Guijarro, David
Martinez, Pedro
Ramon, Diego J.
Yus, Miguel
The reaction of different allylic and benzylic non-enolisable esters or amides (1), carbonates (4), carbamates (6, 7) and ureas (8) with an excess of lithium powder and a catalytic amount of naphthalene (10%) in the presence of an electrophile [(i)PrCHO, (t)BuCHO, PhCHO, Me2CO, Et2CO, (CH2)5CO, Ph2CO, Me3SiCl] in THF at different temperatures (-78, -30 or 0°C) leads, after hydrolysis with water to the corresponding allylated or benzylated products (2).
View MoreNanjing Chemzam Pharmtech Co., Ltd.
Contact:+86-25-86462165,+86-13915979898
Address:C5-1,6 Maiyue Road,Maigaoqiao,Nanjing,Jiangsu,China
Nanjing Vincero International Trading Co.,Ltd
Contact:8618936897229
Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Contact:+86-15995924277
Address:WuZhongOu suzhou new south road 89
Tianjin Boron PharmaTech Co.,Ltd.
Contact:86-022-59845187
Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
Yancheng Smiling Imp & Exp Co., Ltd.
Contact:+86-515-83173586
Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Doi:10.1039/P19960001987
(1996)Doi:10.1016/S0022-328X(00)90592-8
(1970)Doi:10.1039/jr9400001239
(1940)Doi:10.1246/bcsj.42.3016
(1969)Doi:10.1021/ja01092a039
(1965)Doi:10.1002/anie.201913042
(2020)