P. Dupau et al. / Tetrahedron: Asymmetry 10 (1999) 3467–3471
3471
5. Conclusion
We have shown that the direct hydrogenation of ene carbamates containing an intracyclic C_C
bond arising from a cyclic ketone, in the presence of Binap–ruthenium catalysts, leads to a complete
conversion into saturated carbamates when an additional coordinating functionality is present in the
starting molecule. The resulting enantiomeric excesses obtained strongly depend on both the structure
of the substrate and the nature of the carbamate.
Acknowledgements
The authors are very grateful to Dr. A. Renaud, J.-C. Souvie and J.-P. Lecouvé from ORIL Industrie
Company for fruitful discussions and financial support.
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