Nucleosides, nucleotides and nucleic acids p. 593 - 601 (2000)
Update date:2022-08-05
Topics:
Ozaki, Hiroaki
Sato, Yuichi
Azuma, Sadaji
Sawai, Hiroaki
2'-Deoxy-2'-S-hexyluridine derivative was synthesized from 2,2'- anhydrouridine and 1-hexanethiol and incorporated into an oligodeoxyribonucleotide. The thermal stability of the duplexes formed by the 2'-S-hexyl modified ODN with either the complementary DNA or RNA strand was decreased compared to the unmodified counterparts.
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