Phosphorus, Sulfur and Silicon and the Related Elements p. 231 - 254 (1998)
Update date:2022-08-05
Topics:
Dujols, Frederic
Jollet, Philippe
Mulliez, Michel
A general scheme of intramolecular nucleophilic catalysis of aminolysis of the heterocycles B is proposed (Figure 2). The requisite heterocycle D, when built with a β aminoamide residue, allows also a repetitive β peptide synthesis, as with α aminoacids (Figure 1). In order to evaluate the feasibility of both schemes, fifteen phosphor(n)diamides (table III) incorporating one residue of β aminoacid, in form of esters 3, acids 5 (models of E, Figure 2), nitrile 11, or hydrazides 12 have been synthesized starting from P(IV) dichlorides 1 (Figure 3). Unexpectedly hydrolysis of nitriles 6 b c leads to β diacids 9 b c with the regular acids 8 b c.
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Doi:10.1021/jo0000527
(2000)Doi:10.1016/0048-3575(73)90023-0
(1973)Doi:10.1021/jo00811a009
(1971)Doi:10.1016/S0020-1693(99)00587-3
(2000)Doi:10.1016/S0040-4039(01)98501-6
(1970)Doi:10.1021/ic9912629
(2000)