Carbohydrate Research p. 33 - 40 (1982)
Update date:2022-08-02
Topics:
Herd, J. Kenneth
Mayberry, William R.
Snell, Robert L.
L-Idaro-1,4-lactone was synthesized by two different, published methods: (1) epimerization of monopotassium D-glucarate by refluxing in aqueous barium hydroxide, and (2) oxidation of L-iditol by heating in dilute nitric acid.The lactone, formed by heat dehydration from aqueous solution at low pH, was purified by paper chromatography, and quantitated by gas-liquid chromatography using inositol as the internal standard.The monolactone inhibited human, seminal-fluid α-L-idosiduronase activity, with either phenyl or 4-methylumbelliferyl α-L-idosiduronic acid as the substrate, to the same degree as D-glucaro-1,4-lactone inhibits α-D-glucosiduranose.
View Morejiangsu senxuan pharmaceutical and chemical co.,ltd
Contact:86-523-87982810
Address:hongqiao industrial zone,taixing,jiangsu china
Contact:+86-28-88523492
Address:714rooms of Time Square, Pujiang County
Contact:+31-24-3886056
Address:Binderskampweg 29 Unit 36
Chiral Quest (Suzhou) Company Ltd
website:http://www.chiralquest.com
Contact:+86-0512-62956066
Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Hangzhou Mole's Science & Technology Co.,Ltd.
Contact:+86-571-56880228
Address:15F Guodu development Building, NO.182 Zhaohui Road
Doi:10.1016/S0040-4020(00)00978-9
(2000)Doi:10.1021/ol902905w
(2010)Doi:10.1039/jr9490001308
(1949)Doi:10.1021/om400380j
(2013)Doi:10.1039/c1ob06116j
(2011)Doi:10.1021/jo001036c
(2001)