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under conventional heating at 100 ꢀC has been established. 10 (a) L. R. Morgan, B. S. Jursic, C. L. Hooper, D. M. Neumann,
Numerous aromatic aldehydes reacted successfully with dime-
done, ethyl acetoacetate and ammonium acetate to afford the
desired products in good to excellent yields with short reaction
times. This method is simple and environmentally friendly.
Mechanistic studies lead to the discovery of an unexpected
reaction toward the synthesis of polyhydroquinolines that
includes a Michael adduct as a key intermediate derived from
the reaction of aldehydes with dimedone.
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Conflicts of interest
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13 D. da Costa Cabrera, S. B. Rosa, F. S. de Oliveira,
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There are no conicts to declare.
Acknowledgements
This work was supported by Department of Chemistry, Faculty
of Science, King Mongkut’s University of Technology
Thonburi. W. P. is grateful to Center of Excellence for Innova-
tion in Chemistry (PERCH-CIC), Office of the Higher Education
Commission, the Ministry of Education for the nancial
support. We also thank Mrs Vannapa Luckanawat for assistance
with GC-MS analysis.
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R. K. Modukuri, A. Kumar, J. Gautam, D. Singh, B. Sridhar
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