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Organic & Biomolecular Chemistry
Page 4 of 5
DOI: 10.1039/C7OB02585H
COMMUNICATION
Journal Name
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On the basis of the present experimental results and previous
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copper and oxygen. At last, following a sequential reduction of 3t,
the desired product 2t was formed in the presence of DBU.
2
3
4
5
6
7
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Scheme 5. Possible mechanism for the formation of 2t
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We have established a simple and practical method for the
synthesis
benzylidenebenzo[b]thiazinones via
of
2-benzylbenzo[b]thiazinones
a
and
copper-catalyzed
2-
(a) W.-S. Huang, R. Xu, R. Dodd, W.
C Shakespeare,
coupling reaction of 2-iodophenylcinnamamides and
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and
2-
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synthetic application and mechanistic studies of DBU is
currently ongoing in our laboratory.
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Acknowledgment
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This work was supported by the Natural Science Foundation of
China (21572051, 21602057), Education Department of Hunan
Province (15A109), Opening Fund of Key Laboratory of Chemical
Biology and Traditional Chinese Medicine Research (Ministry of
Education of China), Hunan Normal University (KLCBTCMR201707,
KLCBTCMR201708) for financial support.
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Notes and references
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4 | J. Name., 2012, 00, 1-3
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