Monatshefte fur Chemie p. 1199 - 1205 (1998)
Update date:2022-08-05
Topics:
Galy, Jean-Pierre
Galy, Anne-Marie
Vichet, Alain
Elguero, Jose
Starting from 4-hydroxyacridin-9(10H)-one (1) and 4-hydroxyacridine-9(10H)-thione (2), a series of bis-derivatives was prepared, among them the bridged bis-acridin-(10H)-ones 9-14 and the bis-mercapto-(9H)-acridines 15-18. The reactivity of the 2-and 4-hydroxy series was compared; it was found that it is harder to demethylate 4-methoxy derivatives than their 2-methoxy analogues.
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