Synlett p. 691 - 692 (1997)
Update date:2022-08-03
Topics:
Jacob
Roumestant
Viallefont
Martinez
A new synthesis of enantiomerically pure γ-hydroxynorvaline is described. The key step involves diastereoselective alkylation of the chiral Schiff base 1 with primary iodo derivatives 2 easily prepared from propylene oxide.
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