Synthetic Communications p. 2901 - 2912 (2006)
Update date:2022-08-03
Topics:
Rao, R. V. Ramana
Tantry, Subramanyam J.
Babu, Vommina V. Suresh
The synthesis of orthogonally protected Fmoc-Dap/Dab (Boc/Z/Alloc)-OH starting from Fmoc-Asp/Glu has been described. The salient features of our synthetic strategy involved formation of Fmoc-Asp/Glu-5-oxazolidinone acids, conversion of acid function to acyl azides, Curtius rearrangement, and hydrolysis of the oxazolidinone group. Copyright Taylor & Francis Group, LLC.
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