Journal of Organic Chemistry p. 9144 - 9155 (2018)
Update date:2022-08-05
Topics:
Huang, Fei-Dong
Xu, Chang
Lu, Dong-Dong
Shen, Dong-Sheng
Li, Tian
Liu, Feng-Shou
We report herein a highly efficient Pd-catalyzed amination by "bulky-yet-flexible" Pd-PEPPSI-IPentAn complexes. The relationship between the N-heterocyclic carbenes (NHCs) structure and catalytic properties was discussed. Sterically hindered (hetero)aryl chlorides and a variety of aliphatic and aromatic amines can be applied in this cross-coupling, which smoothly proceeded to provide desired products. The operationally simple protocol highlights the rapid access to CAr-N bond formation under mild conditions without the exclusion of air and moisture.
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Doi:10.1016/j.ejmech.2005.10.012
(2006)Doi:10.1021/jo01051a033
(1962)Doi:10.1007/BF00855320
()Doi:10.3987/COM-01-9338
(2001)Doi:10.1016/S0022-328X(03)00322-X
(2003)Doi:10.1002/1099-0690(200110)2001:20<3879::AID-EJOC3879>3.0.CO;2-K
(2001)