Synthetic Communications p. 2633 - 2639 (2007)
Update date:2022-08-03
Topics:
Vasanthakumar, Ganga Ramu
Bhor, Vikrant M.
Surolia, Avadhesha
A simple and efficient method for the synthesis of 7,8-diaminopelargonic acid, a key intermediate in the biotin biosynthesis pathway, is reported. The d-desthiobiotin powder was dissolved in concentrated hydrochloric acid, and the solution was exposed to microwave radiation of 2.45 GHz for varying lengths of time ranging from 60 s to 2 min. The product thus obtained was characterized by spectroscopic techniques and confirmed through bioassay. Further, the protocol was extended to the synthesis of several diamines from their corresponding cyclic ureas. The results show that the method is generally applicable and not only accelerates the hydrolysis reaction but also offers excellent yields. Copyright Taylor & Francis Group, LLC.
View MoreZiBO KuoDing Trade company Ltd
website:http://www.sdzbkd.com
Contact:86-13361591822
Address:GongQingTuan road
Jiangsu Chunjiang AgroChemical Co.,Ltd.
Contact:+86-13817348163
Address:Panjiawan 84, Zhixi Town, Jintan City, China
FUJIAN SHANSHUI CHEMICAL CORP.LTD.
Contact:+86-151-59920036
Address:Jinqiao Gareden, jo@fj-xinyi.com
Contact:+86-310-7092106
Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
website:http://www.china-sinoway.com
Contact:+86-592-5853819
Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
Doi:10.1002/anie.201707716
(2017)Doi:10.1055/s-2007-966001
(2007)Doi:10.1016/0022-328X(94)05068-M
(1995)Doi:10.1039/c39950000223
(1995)Doi:10.1021/ol501655g
(2014)Doi:10.1021/ic00114a042
(1995)