Journal of Medicinal Chemistry p. 421 - 430 (1977)
Update date:2022-09-26
Topics:
Christy
Colton
Mackay
Staas
Wong
Engelhardt
Torchiana
Stone
Upon finding 2-(α,α,β,β-tetrafluorophenethyl)benzylamine (4) to be a potent and novel type of antiarrhythmic agent, 2-, 3-, and 4-(α,α,β,β-Tetrafluorophenethyl) benzylamines were synthesized. Structure-activity relationships in this series are described.
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