Journal of Organic Chemistry p. 2125 - 2130 (1984)
Update date:2022-08-05
Topics:
Apparu, Marcel
Crandall, Jack K.
Allenyl halides of structure (CH3)2C=C=CH(CH2)nX with n=3-6 have been prepared and reacted with n-Bu3SnH to generate the corresponding radicals for examination of the cyclization reactions of these reactive intermediates.The observed hydrocarbon products indicate that cyclization occurs for the n=3,4, and 5 radicals but not for the n=6 species.The n=3 radical isomerizes very efficiently by intramolecular addition to the sp carbon of the allene group.The n=5 intermediate reacts relatively slowly by attack at the near sp2 carbon.Both cyclization modes are observed for the n=4 species.The details of these radical cyclizations are discussed.
View MoreShanghai Anya Chemicals Co.,Ltd
Contact:+86 21 51087925
Address:Room 1101, No.1, Lane 111, Fudu Road, Shanghai, China
Jinan Yijialian Economic and Trade Development Co., Ltd.
Contact:+86 0531-66729596
Address:jinan
Hubei Lansun Biochemical Pharmaceutical Co., Ltd
Contact:714-6395977
Address:No. 81 Pengcheng Avenue, economic and technological development zone, Huangshi City, Hubei Province,China
website:http://www.hanwayschem.com
Contact:+86-18502787239(whatsapp)
Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
Anhui New Star Pharmaceutical Development Co., Ltd
Contact:013956922763
Address:Floor 3, F9A, F Workshop, No.110 Kexue Road, High-Tech Development Zone, Hefei, Anhui ,China
Doi:10.1039/b108735p
(2002)Doi:10.1248/yakushi1947.93.3_391
(1973)Doi:10.1246/bcsj.46.1539
(1973)Doi:10.1021/jm00330a002
(1965)Doi:10.1021/jo0159082
(2002)Doi:10.1016/S0040-4020(01)93918-3
()