Journal of the American Chemical Society p. 2186 - 2193 (1989)
Update date:2022-08-05
Topics:
Clemens, Robert J.
Witzeman, Stewart J.
Acetylketene is shown to be a reactive intermediate in thermolytic reactions of 2,2,6-trimethyl-4H-1,3-dioxin-4-one (the diketene-acetone adduct) via a series of kinetic studies.The uncatalyzed acetoacetylations of phenol, 1-butanol, and di-n-butylamine with the title dioxinone at 82-107 deg C are first-order reactions in which the rate-limiting step is the formation of acetylketene and acetone, presumably via a retro-Diels-Alder reaction.Isopropenyl acetoacetate is not an intermediate in the aforementioned reactions but also provides acetylketene when heated.Acetylketene was observed by FT-IR spectroscopy in an argon matrix.
View MoreZhejiang Tianyu Pharmaceutical Co., Ltd.
Contact:+86-576-84177669, 89189665,89189688,84168770
Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Henan zhongda Biological Engineering Co., Ltd
Contact:86-28-18109029985
Address:shenzhou road,xuedian industrial estate,zhengzhou city,henan province CHN
Contact:+ 86 512 52491118
Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Tianjin Dongchang Fine Chemical Industry Co., Ltd.
Contact:+86-22-29894595
Address:Economic Developing Zone, Ji County, Tianjin, China
Contact:0510-85393305
Address:1619 Huishan Avenue, Huishan District, Wuxi,
Doi:10.1023/A:1020933900167
(2002)Doi:10.1016/j.bmc.2013.12.011
(2014)Doi:10.1016/S0968-0896(01)00428-X
(2002)Doi:10.1007/s12149-021-01669-6
(2021)Doi:10.1016/0022-1902(66)80313-5
(1966)Doi:10.1016/S0040-4039(02)00335-0
(2002)