trifluoroacetates, or allylic acetates is a new, high-yielding alter-
native for the synthesis of dimeric molecules from
convenient, bench-stable starting materials.
13 For an example of an organoboron reagent with ketone
functionality, see: (a) J. A. Zablocki, J. A. Katzenellenbogen,
K. E. Carlson, M. J. Norman and B. S. Katzenellenbogen,
J. Med. Chem., 1987, 30, 829–838; for the coupling of
functionalized alkylborane reagents with primary alkyl bromides,
This work was supported by startup funds from the
University of Rochester and a Graduate Research Fellowship
from the National Science Foundation to D. A. Everson.
Acknowledgement is also made to the Donors of the American
Chemical Society Petroleum Research Fund for partial
support of this research.
see: (b) M. R. Netherton, C. Dai, K. Neuschutz and G. C. Fu,
J. Am. Chem. Soc., 2001, 123, 10099–10100.
¨
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see: J. Terao, H. Watanabe, A. Ikumi, H. Kuniyasu and
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This journal is The Royal Society of Chemistry 2010
Chem. Commun., 2010, 46, 5743–5745 | 5745