Bioorganic and Medicinal Chemistry Letters p. 2986 - 2989 (2017)
Update date:2022-08-04
Topics:
Verhasselt, Sigrid
Stevens, Christian V.
Van den broecke, Tom
Bracke, Marc E.
Roman, Bart I.
Myosin II is an interesting target for therapeutic intervention, as it is involved in a large number of motility-based diseases. (S)-Blebbistatin is a known micromolar inhibitor of this protein. A new series of (S)-blebbistatin derivatives with a modified
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