Synthetic Communications p. 3005 - 3010 (2001)
Update date:2022-08-02
Topics:
Mereyala
Koduru
Synthesis of 2-amino-1-(4′-methoxyphenyl)-propane (II) starting from p-anisaldehyde (1) in 67% overall yield is described. Key reactions involved Horner-Wadswoth-Emmons olefination of 1 to form the ester 2 and Hoffmann degradation of amide 5 to obtain the amine II.
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Doi:10.1021/ja9033473
(2009)Doi:10.1039/b902210d
(2009)Doi:10.1016/0040-4039(88)85060-3
(1988)Doi:10.1016/0040-4039(88)85071-8
(1988)Doi:10.1039/b907536d
(2009)Doi:10.1021/ic9006108
(2009)