Bioconjugate Chemistry
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(15) Arosio, D., Fontanella, M., Baldini, L., Mauri, L., Bernardi, A., Casnati, A.,
Sansone, F., and Ungaro, R. (2005) A Synthetic Divalent Cholera Toxin
Glycocalix[4]arene Ligand Having Higher Affinity than Natural GM1
Oligosaccharide Scheme 1. Synthesis of the Divalent Ligand 1. J. Am. Chem.
Soc. 127, 3660–3661.
The authors declare no conflict of interest.
SUPPORTING INFORMATION
(16) Cheshev, P., Morelli, L., Marchesi, M., Podlipnik, Č., Bergström, M., and
Bernardi, A. (2010) Synthesis and affinity evaluation of a small library of
bidentate cholera toxin ligands: Towards nonhydrolyzable ganglioside mimics.
Chem. Eur. J. 16, 1951–1967.
The Supporting Information is available free of charge on the ACS
Publications website at DOI:
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Experimental details, NMR , inhibition curves for ELISA assay,
inhibition curves for organoid assay and IR spectra.
(17) Leaver, D. J., Hughes, A. B., Dawson, R. M., Postma, A., Malic, N., and
Polyzos, A. (2014) Synthesis of RAFT polymers as bivalent inhibitors of
cholera toxin. RSC Adv. 4, 14868–14871.
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