Tetrahedron p. 2125 - 2136 (1997)
Update date:2022-07-30
Topics:
Dell'Erba, Carlo
Novi, Marino
Petrillo, Giovanni
Tavani, Cinzia
The reactions of arylazosulfones 1 (ArN = NSO2Ar') with the potassium salts of (tert-butoxycarbonyl)methyl 2 and tosylmethyl isocyanide 3 in DMSO afford 4,5-bis(tert-butoxycarbonyl)- 4 and 4-tosyl-1-arylimidazoles 5, respectively. Yields of imidazoles 4 and 5 vary from moderate to excellent depending on the nature both of Ar in 1 and of the nucleophile (2 or 3) employed. A comparison of the results obtained with those relevant to the reactions of the same nucleophiles with nitrosobenzene in analogous experimental conditions provides useful mechanistic indications on the transformation of 1 to 4 or 5.
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Doi:10.1021/jo01127a021
(1955)Doi:10.1021/ja00506a020
(1979)Doi:10.1016/j.ejmech.2011.04.021
(2011)Doi:10.1016/S0022-328X(01)01103-2
(2002)Doi:10.1002/hlca.19760590233
(1976)Doi:10.1016/S0040-4039(97)10174-5
(1997)