Organic Letters p. 5260 - 5263 (2018)
Update date:2022-07-29
Topics:
Wang, Kezhou
Chen, Chao
Liu, Xihong
Li, Dan
Peng, Tianyu
Liu, Xin
Yang, Dongxu
Wang, Linqing
A series of 2-(cyanomethyl)azaarenes containing benzothiazole or benzoxazole were designed and synthesized for asymmetric α-functionalization with N-Boc-amino sulfones. The Mannich adducts were obtained in high yields with good diastereo- and enantioselectivities. Aryl-substituted amino sulfones were tolerated under the current conditions, and the reaction can be performed on gram scale in good results.
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Doi:10.1515/znb-2002-1115
(2002)Doi:10.1007/BF00926439
()Doi:10.1016/S0022-328X(00)89711-9
(1977)Doi:10.1016/S0040-4039(01)87316-0
(1973)Doi:10.1002/jps.2600620729
(1973)Doi:10.1016/j.bmcl.2017.11.048
(2018)