Tetrahedron Letters p. 2103 - 2106 (1998)
Update date:2022-08-04
Topics:
Cristau
Darviche
Torreilles
Fabre
We studied the influence of acetic acid concentration on the deamination and dephogphonylation of the adduct resulting of the nucleophilic reaction between adequate α-metalated phosphonate and imminium salt, to enhance the yield of such reactions in order to access efficiently a lot of unsymmetrical TTF derivatives. A mechanism is proposed for the formation of TTF, including steps, i1 to i7. The potential concurrent formation of phosphonate 1 and other by-products is also discussed.
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Doi:10.1021/jf60184a026
(1972)Doi:10.1016/S0022-328X(00)90668-5
(1977)Doi:10.1039/b401172d
(2004)Doi:10.1016/j.jorganchem.2003.08.045
(2003)Doi:10.1021/jf60216a020
(1978)Doi:10.1039/c8gc01411f
(2018)