Organic Letters
Letter
(8) Zhao, J.; Yang, S.; Xie, X.; Li, X.; Liu, Y. J. Org. Chem. 2018, 83,
1287−1297.
AUTHOR INFORMATION
■
Corresponding Author
ORCID
(9) For gold-catalyzed annulations or cycloadditions of alkynes, see
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9, 3066.
Notes
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3357−3363.
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The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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The authors thank the Ministry of Science and Technology
and the Ministry of Education, Taiwan, for supporting this
work.
(13) Besides our proposed mechanism, the following mechanism is
also likely to occur. Initial species B undergoes an elctrocyclization to
form a gold-containing allylic cation F that reacts with anthranil in a
[4 + 3]-annulation to yield a seven-membered oxonium intermediate
G. A further ring opening of species G yields the observed product 3a.
This alternative mechanism rationalizes our crossover experiments,
and the reaction stereochemistry matches well with our observation.
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