Chemical and Pharmaceutical Bulletin p. 4914 - 4922 (1984)
Update date:2022-08-02
Topics:
Hayakawa
Suzuki
Suzuki
Tanaka
As a part of our search for new antibacterial agents, 5-ethyl-8-oxo-5,8-dihydrofuro[3,2-b][1,8]naphthyridine-7-carboxylic acid and its 2,3-dihydrofuro derivative, the 4-aza analogue of droxacin, were synthesized and their antibacterial activities were tested. Both compounds exhibited high antibacterial activities and a broad antibacterial spectrum. In an attempt to find a suitable method for industrial-scale synthesis of these compounds, several methods for the furan ring cyclization of 6,7-disubstituted 1,8-naphthyridine-3-carboxylate derivatives were compared.
View MorePuyang Huicheng Electronic Material Co., Ltd
website:http://huichengchem.weba.testwebsite.cn/index_en.html
Contact:+86-393-8910800
Address:West Section Shengli Road, Puyang457000, China
Nanjing distinctions Medical Technology Co., Ltd.
Contact:+86-15996203785 13914714059
Address:nanjing,jiangsu , China
Contact:+86-571-86491666
Address:SHI XIANG ROAD
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Contact:86-574-83851061 86-574-87083208
Address:Room 905, No.3 Building,East Business Center, 456 Xingning Road, Ningbo City,China
Doi:10.1021/ja00521a100
(1980)Doi:10.1002/ejoc.200400047
(2004)Doi:10.1016/j.tetlet.2014.01.024
(2014)Doi:10.1021/jo01299a041
(1980)Doi:10.1021/ja01624a036
(1955)Doi:10.1002/ardp.19793121202
(1979)
