Journal of Organic Chemistry p. 98 - 101 (1983)
Update date:2022-08-05
Topics:
Sato, Tadao
Ueda, Hiraki
Nakagawa, Kazuyuki
Bodor, Nicholas
An efficient asymmetric synthesis of the enantiomers of cyclophosphamide was developed on the basis of three importand steps: (1) a highly stereospecific synthesis of the 2-chloro-2-oxo-1,3,2-oxazaphosphorinane ring from an optically active amino alcohol
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