Journal of Medicinal Chemistry p. 998 - 1000 (1981)
Update date:2022-08-02
Topics: Chemical Synthesis Anti-Inflammatory Structure-Activity Relationship Experimental Design In vitro assay 2-(Arylmethyl)arylacetic Acids Inflammatory mediators In vivo study
Brancaccio, Giovanni
Larizza, Angelo
Lettieri, Guglielmo
Monforte, Pietro
The title compounds 2 have been synthesized and tested for antiinflammatory activity.The synthetic method, consisting of the chemical sequence 3-aryl-1H-indenes (4) <*> 2-(aroyl)arylacetic acids (5) <*> 2, appears to be of value because of its simplicity
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