Tetrahedron p. 747 - 751 (1981)
Update date:2022-08-04
Topics:
Jacquesy, J. C.
Jouannetaud, M. P.
In SbF5-HF, reaction of bromine with 2,6-dimethylphenol gives the meta bromo compound 1b which is further halogenated to 3,4-dibromo-2,6-dimethylphenol 1c.In the same conditions ether 2a yields successively 2b and 2d.Meta bromination of compounds 1a, 2a, 2b implies electrophilic attack on the O-protonated substrate, whereas reaction of the neutral phenol 1b leads to the p-bromoderivative 1c.All products are obtained in excellent yields (>85 percent).
View MoreZhenjiang Haitong Chemical Industry Co., Ltd.
Contact:+86 (511) 8448-0369
Address:Baoyan Town, Dantu District, Zhenjiang City, Jiangsu, China
Contact:+86-21-38682181
Address:shanghai ,china
Jiaxing Trustworthy Import And Export Co.,Ltd
Contact:+86-573-82030555
Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
Shuanghe Bio-Technology Limited
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Contact:+86-0592 5353131
Address:No.56 Guani Road Software Park 2,Siming District
Doi:10.1016/0040-4039(91)80226-V
(1991)Doi:10.1002/chem.201403248
(2014)Doi:10.1021/jo00337a013
(1981)Doi:10.1016/S0040-4039(01)91270-5
(1984)Doi:10.1139/V07-153
(2008)Doi:10.1080/00397910600948088
(2006)