Synthetic Communications p. 4113 - 4122 (1996)
Update date:2022-08-06
Topics:
Benincasa, Marta
Forti, Luca
Ghelfi, Franco
Libertini, Emanuela
Pagnoni, Ugo M.
Methyl 2,2-dihalocarboxylates add easily to carbonyl compounds in fair to good yields through the intermediate formation of 2-haloester enolates; the reaction is promoted by zinc, following a "Barbier" type procedure.
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