Journal of the Chemical Society. Perkin transactions I p. 3242 - 3249 (1981)
Update date:2022-08-04
Topics: Characterization Purification Final steps Stereochemistry Control Starting Materials Purification and Analysis Ring Expansion Functional Group Manipulations Oxidation and Reduction Further Elaboration
Bateson, John H.
Baxter, Andrew J. G.
Roberts, Patricia M.
Smale, Terence C.
Southgate, Robert
4-Allylazetidin-2-one, prepared from penta-1,4-diene and chlorosulphonyl isocyanate, has been used to synthesise the parent 7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate system of the naturally occurring olivanic acids, using an intramolecular Wittig reaction to construct the 2,3-double bond.Cyclisation of ketones derived from the 4-allyl grouping produced 3-substituted derivatives, while use of the azetidin-2-one prepared from hexa-1,5-diene and chlorosulphonyl isocyanate has given the homologous 8-oxo-1-azabicyclo<4.2.0>oct-2-ene system.
View MoreShandong Zhongcheng Barium Salt Co., Ltd
Contact:+86-15725732638
Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Shao Xing Empire Import&Export CO.,ltd
Contact:86-575-82127757
Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
Changzhou Sunlight Pharmaceutical Co., Ltd.
Contact:+86-519-83131668;83139028;83138042;83137041
Address:JiuliStreet, Benniu Town Changzhou City, Jiangsu Province
Shanghai Yuantai Chemical Products Co., Ltd
Contact:021--66129803
Address:Chengyin Road,Shanghai,China
Contact:+(852) 301-98033
Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
Doi:10.1016/j.carres.2017.10.014
(2017)Doi:10.1039/c3ob26909d
(2013)Doi:10.1246/cl.1982.411
(1982)Doi:10.1016/j.farmac.2004.05.006
(2004)Doi:10.1002/anie.201107490
(2012)Doi:10.1016/S0040-4020(01)90617-9
(1986)