Chemistry of Heterocyclic Compounds p. 58 - 61 (1982)
Update date:2022-07-29
Topics:
Marchenko
Granik
The reaction of butyrolactone acetal with CH acids was used to synthesize 2-methylenetetrahydrofuran derivatives. The latter react with dimethylformimide acetal to give a dieneamine that is capable of undergoing cyclization to furo [3,2-c]pyrimidine derivatives. This two-ring system was also synthesized by the reaction of cyanacetamide with 3-dimethylaminomethylenebutyrolactone acetal. The indicated acetal can also react with amidine components to give furo [2,3-d]pyrimidine derivatives.
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Doi:10.1016/S0040-4039(01)92496-7
(1981)Doi:10.1002/hlca.200490235
(2004)Doi:10.1002/adsc.200404151
(2005)Doi:10.1021/ic50045a029
(1966)Doi:10.1023/B:COHC.0000023762.58036.6d
(2004)Doi:10.1021/jm00348a010
(1982)