Steroids p. 727 - 738 (1989)
Update date:2022-08-03
Topics:
Yoshida, Hirokazu
Nakai, Shiro
Nimbari, Fusako
Yoshimoto, Kiyoko
Nishimura, Tadashi
C-4 and C-6 bridged haptens of 11α-hydroxyprogesterone, an anti-androgen, were respectively synthesized via 4,5 and 5α,6α epoxide ring openings using 3-mercaptopropanoic acid.Substitution of 6-bromo derivative of progesterone using the same reagent unexpectedly afforded a C-4 substituted product instead of the normal C-6 substituted product previously reported in the literature.
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Doi:10.1039/a806714g
(1999)Doi:10.1016/S0020-1693(00)90330-X
(1982)Doi:10.1002/mrc.1270180207
(1982)Doi:10.1021/jacs.7b05155
(2017)Doi:10.1021/acs.orglett.6b01647
(2016)Doi:10.1002/hlca.19820650220
(1982)