Synthetic Communications p. 989 - 1001 (1999)
Update date:2022-08-04
Topics:
Fox, Raymond C.
Taylor, Paul D.
N-alkyl-3-hydroxy-2-methyl-4(1H)-pyridinones can be synthesised in reasonable yield from either 1-(3-hydroxy-2-furanyl)ethanone or O- galactosylisomaltol. Since these carbohydrate precursors can be produced from the disaccharide, α-D-lactose, a simple and inexpensive transformation into pyridinones is possible.
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