Chemistry of Heterocyclic Compounds p. 703 - 706 (1982)
Update date:2022-08-04
Topics:
Portnov, Yu. N.
Zabrodnyaya, V. G.
Voronin, V. G.
Kost, A. N.
The reaction of N-phthalyl-β-aryl-β-alanine N'-methyl-N'-phenylhydrazides with phosphorus oxychloride (at cca 80 deg C) is accompanied by further transformations of the initially formed 2-aminoindole derivatives and leads to isoindolo<1',2':2,3>pyrimido<5,6-b>indole derivatives.Intermediate 2-aminoindoles were isolated at lower reaction temperatures.The hydrolysis of the isoindolo<1',2':2,3>pyrimido<5,6-b>indole derivatives was studied.The structures of the compounds obtained were established on the basis of the PMR, IR, and UV spectra and the results of elementary analysis.
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Doi:10.1021/ac00251a013
(1982)Doi:10.1039/b713167d
(2007)Doi:10.1039/c39820000609
(1982)Doi:10.1021/ja00388a041
(1982)Doi:10.1111/0002-9092.00159
(1947)Doi:10.1021/jo00140a034
(1982)