Heterocycles p. 437 - 446 (2004)
Update date:2022-09-26
Topics:
Young, Robert N.
Billot, Xavier
Han, Yongxin
Slipetz, Deborah A.
Chauret, Nathalie
Belley, Michel
Metters, Kathleen
Mathieu, Marie-Claude
Greig, Gillian M.
Denis, Danielle
Girard, Mario
An optimized analog of prostaglandin E2 which incorporates a γ-lactam in place of the cyclopentanone ring and which incorporates metabolically stabilized side chains, has been identified and shown to exhibit potent and selective EP4 receptor ag
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