European Journal of Medicinal Chemistry p. 837 - 852 (1993)
Update date:2022-07-31
Topics:
Werbel, L. M.
Kesten, S. J.
Turner, W. R.
Structure-activity relationships have been ascertained and chemical metodology developed for a series of antimalarial 3-chloroindolo<3,2-c>quinoline-5-oxides.The basic side chain as well as the ring N-oxide are critical for antimalarial activity as is a bromine or chlorine in position 3.Substitution at positions 7,8,9,10 in not essential, although the most potent analog in our studies was the 8-nitro compound 4vv. indolo<3,2-c>quinolines <1,2> / antimalarial agents
View MoreShanghai Mintchem Development ., Ltd
Contact:0086 21 5190 8570
Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Wuhan Konberd Biotech Co., Ltd.
Contact:+86-27-87205925
Address:NO.666, Gaoxin Road, Eastlake High-tech zone
HEZE KINGVOLT CHEMICAL CO., LTD
Contact:86-573-82118911
Address:Juancheng Industry Park
Wuxi Pharma-Trading Import & Export Co.,Ltd.
Contact:+86-510-82304590 82716390
Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
Tianjin Pharmacn Medical Technology Co.,Ltd.
Contact:86-22-60122566ext.866(English),23359620
Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Doi:10.1248/cpb.27.2207
(1979)Doi:10.1016/j.poly.2004.03.017
(2004)Doi:10.1016/S1872-2067(11)60330-6
(2012)Doi:10.1039/c7gc03864j
(2018)Doi:10.1016/j.bmc.2020.115961
(2021)Doi:10.1016/S0040-4039(01)93588-9
(1979)