Tetrahedron Letters p. 2693 - 2696 (1983)
Update date:2022-07-29
Topics: Ester Nucleophile Rearrangement Clavulanic acid Dichloroacetate Ring cleavage BF3 etherate Thioether Neutral Conditions Acidic Conditions Basic Conditions
Brown
Howarth
Ponsford
Investigations into the chemistry of benzyl clavulanate under a variety of reaction conditions has led to acid catalysed one-step conversion to ether and thioether derivatives. Generation of nitrogen-containing displacement products proceeds via the react
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