Carbohydrate Research p. 21 - 30 (1983)
Update date:2022-08-04
Topics:
Rasmussen, James R.
Tafuri, Sherrie R.
Smale, Stephen T.
Addition of potassium cyanide to 2-deoxy-2-fluoro-D-arabinose (1) at pH 7.8 followed by catalytic hydrogenation over palladium-barium sulfate (5percent) produced 3-deoxy-3-fluoro-D-glucose (4) and 3-deoxy-3-fluoro-D-mannose (5) in 25 and 40 percent isolated yields, respectively.The epimeric sugars were purified by passage through a column of Dowex-50W x 8 (Ca2+).In a similar manner, 3-deoxy-3-fluoro-D-arabinose (6) was converted into 4-deoxy-4-fluoro-D-glucose (9) and 4-deoxy-4-fluoro-D-mannose (10) in 27 and 45 percent isolated yields, respectively.Deoxyfluorohexoses 4,5,9 and 10 enriched with carbon-13 and crbon-14 at C-1 have been prepared by this procedure.
View MoreContact:886 2 2541 0022
Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd
website:http://www.tianpharm.com
Contact:86-755-23284190
Address:B302,2 unit, Jin Lian Building, No. 134 Qianjin 2 Road, Taoyuan village, Xixiang Street, Baoan,Shenzhen,China
Sanming Coffer Fine Chemical Industrial Co., Ltd
website:http://www.cofferxm.com/
Contact:+86-598-5853979
Address:Jin-sha Yuan Chuang-ye Park,Hi-Tech Development Zone,Sanming City P.R.China
Shenzhen Sunrising Industry Co., ltd.
Contact:+86 755 86571158 / 86571159 / 86571160
Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
Zhuzhou Farshine Chemical Industry Co., Ltd
Contact:0086-731-28482786
Address:No. 1,Shui Xian Road, He Tang Dictrict,Hunan-412000,China
Doi:10.1248/cpb.42.802
(1994)Doi:10.1021/ic051487l
(2006)Doi:10.1016/j.ejmech.2013.10.030
(2013)Doi:10.1002/ejic.201100119
(2011)Doi:10.1021/jf048994q
(2005)Doi:10.1016/j.bmc.2009.01.023
(2009)