10
S. A. I. QUADRI ET AL.
and the separated organic phase was washed with water. Solvent was distilled out under
reduce pressure at 50 °C. The product was isolated by crystallization in isopropyl alcohol
(30 mL) and conc. hydrochloric acid (1.91 g) followed by filtration and drying to yield
5.76 g hydrochloride salt as white solid, m.p 240 °C–244 °C. IR (cm−1)): 3105, 2924,
1
2231, 1567, 1533, 1460; H NMR (400 MHz, DMSO) δ: 0.98 (3H, t, CH3), 3.05(2H, q,
CH2) 7.26 (1H, t, Ar-CH); 7.4 (1H, t, Ar-CH); 7.72(1H, d, Ar-CH); 7.91(1H, d, Ar-CH);
8.12(1H, d, Ar-CH); 8.21(1H, d, Ar-CH); 8.40(1H, s, Ar-CH). HRMS (ESI) for
C17H12F3N3S [MþH]þ: 348.3102, Anal. Calcd for C17H12F3N3S: C, 58.78; H, 3.48; N,
12.10 Found: C, 58.75; H, 3.45; N, 12.10.
Acknowledgment
We acknowledge the management of Dr. Rafiq Zakaria College for women Aurangabad.
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