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Chemical Science
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Journal Name
ARTICLE
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DOI: 10.1039/D0SC01445A
Kappe, D. Cantillo, Chem. Eur. J. 2018, 24, 17234.
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7
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R
LNi(I)-Br
ArBr
C
Ar-LNi(III)-Br
-e-
A
- H+
Ar-LNi(III)-Br
Br
+e-
R
R
anode
FTO
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Ar-LNi(II)-Br
LNi(0)
Cathode
ArBr
B
Carbon firbre
Scheme 1. Proposed mechanism of the direct arylation of
benzylic C-H bond
Conclusions
In summary, by integrating Ni-catalyzed benzyl-aryl coupling
into paired electrolysis, we achieved direct arylation of benzylic
C−H bonds under simple electrochemical conditions. The direct
arylation method has broad scope and high functional group
tolerance, giving access to a diverse range of diarylmethanes.
Our work demonstrates the utility of metal catalysis in
convergent paired electrolysis, which has many untapped
potentials in organic electrosynthesis.
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Acknowledgements
This work is supported by the European Research Council
(no.681292).
Notes and references
1
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