Journal of the American Chemical Society
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In conclusion, we have developed an efficient method for the
para-selective borylation of esters using a designed iridium
catalyst having a L-shaped ligand with a pendant non-covalent
interacting site. The essential feature of this borylation is the
non-covalent interaction between the substrate and the cata-
lyst, which primarily controls the selectivity. The developed
method shows very broad substrate scope and functional group
tolerance. More efforts are underway in our laboratory.
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R. J. Am. Chem. Soc. 2017, doi: 10.1021/jacs.7b02232.
ASSOCIATED CONTENT
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Supporting Information Available: Full characterization, copies
of all spectral data, experimental procedures. This material is
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AUTHOR INFORMATION
Corresponding Author
buddhadeb.c@cbmr.res.in, buddhachem12@gmail.com
Author Contributions
(13) (a) Kuninobu, Y.; Ida, H.; Nishi, M.; Kanai, M. Nat. Chem.
2015, 7, 712. (b) Bisht, R.; Chattopadhyay, B. J. Am. Chem. Soc.
2016, 138, 84. (c) Davis, H. J.; Madalina, M. T.; Phipps, R. J. J. Am.
Chem. Soc. 2016, 138, 12759.
MEH and RB contributed equally.
Notes
(14) For para functionalization, see: (a) Wang, X.; Leow, D.; Yu,
J.-Q. J. Am. Chem. Soc. 2011, 133, 13864. (b) Karthikeyan, J.; Chen,
C.-H. Angew. Chem. Int. Ed. 2011, 50, 9880. (c) Bag, S.; Patra, T.;
Modak, A.; Deb, A.; Maity, S.; Dutta, U.; Dey, A.; Kancherla, R.;
Maji, A.; Hazra, A.; Bera, M.; Maiti, D. J. Am. Chem. Soc. 2015, 137,
11888. (d) Patra, T.; Bag, S.; Kancherla, R.; Mondal, A.; Dey, A.;
Pimparkar, S.; Agasti, S.; Modak, A.; Maiti, D. Angew. Chem. Int. Ed.
2016, 55, 7751. (e) Boursalian, G. B.; Ham, W. S.; Mazzotti, A. R.;
Ritter, T. Nat. Chem. 2016, 8, 810. (e) Luan, Y.-X.; Zhan, T.; Yao,
W.-W.; Lu, K.; Kong, L.-Y.; Lin, Y.-T. J. Am. Chem. Soc. 2017, 139,
1786.
The authors declare no competing financial interest.
ACKNOWLEDGMENT
This work was supported by DST-Ramanujan Fellowship
(SB/S2/RJN-45/2013) and Young Scientist Grant (SB/FT/CS-
141/2014). RB thanks DST for SRF and MEH thanks UGC for
JRF. We thank Dr. Baishya and Mr. Verma for NMR analysis,
Mr. Pushpendra and Mr. Prashant for HRMS and the Director,
CBMR for research facility.
(15) (a) Saito, Y.; Segawa, Y.; Itami, K. J. Am. Chem. Soc. 2015,
137, 5193. (b) Haines, B.; Saito, Y.; Segawa, Y.; Itami, K.; Musaev,
D. G. ACS Catal. 2016, 6, 7535.
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