Journal of the American Chemical Society p. 6060 - 6074 (1984)
Update date:2022-08-05
Topics:
Pearson
Kole
Ray
Whereas the reactions of tricarbonylcycloheptadienyliron salts with nucleophiles generally occur in low yield giving mixtures of products, the corresponding dicarbonyl(triphenylphosphine) and dicarbonyl(triphenyl phosphite) complexes 8 give high yields of single adducts on reaction with a range of nucleophiles. The regioselectivity of nucleophile addition to 8 is strongly dependent on the nucleophile, 'soft' nucleophiles attacking C-1, 'hard' nucleophiles attacking C-2 of the dienyl ligand. The diene complexes 10 resulting from C-1 addition can be reactivated by hydride abstraction with Ph//3C** plus PF//6** minus , to give dienyl complexes 11, which undergo a second nucleophile addition regio- and stereospecifically (trans to the Fe(CO)//2L group). Decomplexation is easily accomplished, leading to cycloheptadienylacetic acid derivatives.
View MoreNanjing Capatue Chemical Co., Ltd
Contact:+86-25-86371192 +86-025-85720158
Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
SJZ Chenghui Chemical Co., Ltd.
Contact:86-311-87713916
Address:no.368 youyi north avenue
Beijing Cooperate Pharmaceutical Co.,Ltd
Contact:86-01060279497
Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Hangzhou Showland Technology Co., Ltd.
Contact:86-571-88920516
Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Guilin Zhenda Bio-Tech Co., Ltd.
Contact:86-773-3568977
Address:-Yangtang shangshui industry park, Lingui county,
Doi:10.1016/j.jfluchem.2005.12.008
(2006)Doi:10.1016/S0040-4020(98)01102-8
(1999)Doi:10.1007/BF00948990
(1984)Doi:10.1016/j.bmc.2006.09.058
(2007)Doi:10.1002/chem.201505135
(2016)Doi:10.1016/S0040-4039(01)90818-4
(1963)