Journal of Organic Chemistry p. 1064 - 1071 (1988)
Update date:2022-08-03
Topics:
Gannett, Peter M.
Nagel, Donald L.
Reilly, Pam J.
Lawson, Terence
Sharpe, Jody
Toth, Bela
Capsaicin (1b), the pungent ingredient in many varietes of Capsicums has recently been implicated as a possible carcinogen.When obtained from natural sources 1b is always accompanied by a number of related homologues.We have isolated seven of these homologues, characterized them, and synthesized them by a general and unique route developed in our laboratories.Also reported are mutagenicity data for 1b and an extract of red pepper as measured by the Ames assay and the V-79 mammalian cell assay.
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