Isoform-SelectiVe Inhibition of UGT2B7
Journal of Medicinal Chemistry, 2007, Vol. 50, No. 11 2663
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Acknowledgment. We thank Sanna Sistonen for conducting
some of the isoform-selectivity assays, Olli Aitio for his help
with the gNOESY experiments, and Sirkku Ja¨ntti for conducting
the LC-MS analyses. This work was supported by a fellowship
from the Finnish Cultural Foundation (IB), a grant from Walter
och Lisi Wahls Stiftelse fo¨r Naturvetenskaplig Forskning, and
the Academy of Finland (Projects 207535 and 210933).
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Supporting Information Available: Degree of purity (elemen-
tal analysis), synthesis procedures, spectroscopic data, X-ray crystal
structures, 1H-13C correlation data, gHSQC and 13C NMR spectra,
and testing for reversibility of inhibition. This material is available
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