Organic Letters
Letter
(10) Lqbal, N.; Choi, S.; Ko, E.; Cho, E. J. Tetrahedron Lett. 2012, 53,
2005.
standing of the reaction mechanism are currently underway in
our laboratory.
(11) The electrophilic trifluoromethylation reaction of anilines with
Togni’s reagent also occured when it was carried out at high
temperature in the presence of Lewis acids. However, the reaction
conditions resulted in a limited scope. See: Wiehn, M. S.; Vinogradova,
E. V.; Togni, A. J. Fluorine Chem. 2010, 131, 951.
(12) (a) Yasu, Y.; Koike, T.; Akita, M. Angew. Chem., Int. Ed. 2012,
51, 9567. (b) Yasu, Y.; Koike, T.; Akita, M. Org. Lett. 2013, 15, 2136.
(c) Mizuta, S.; Verhoog, S.; Engle, K. M.; Khotavivattana, T.;
ASSOCIATED CONTENT
* Supporting Information
■
S
Experimental procedures, characterization data, crystallographic
data for CCDC 958619 (14) and 953716 (32) (CIF), NMR
spectra of products. This material is available free of charge via
O’Dui00ll, M.; Wheelhouse, K.; Rassias, G.; Med
́
ebielle, M.;
Gouverneur, V. J. Am. Chem. Soc. 2013, 135, 2505.
AUTHOR INFORMATION
Corresponding Authors
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(13) (a) Nagib, D. A.; Scott, M. E.; MacMillan, D. W. C. J. Am. Chem.
Soc. 2009, 131, 10875. (b) Iqbal, N.; Jung, J.; Park, S.; Cho, E. J.
Angew. Chem., Int. Ed. 2014, 53, 539.
(14) (a) Ji, Y.; Brueckl, T.; Baxter, R. D.; Fujiwara, Y.; Seiple, I. B.;
Su, S.; Blackmond, D. G.; Baran, P. S. Proc. Natl. Acad. Sci. U.S.A.
2011, 108, 14411. (b) Wilger, D. J.; Gesmundo, N. J.; Nicewicz, D. A.
Chem. Sci. 2013, 4, 3160.
Notes
The authors declare no competing financial interest.
(15) Wu, X.; Chu, L.; Qing, F.-L. Angew. Chem., Int. Ed. 2013, 52,
2198.
ACKNOWLEDGMENTS
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(16) (a) Parsons, A. T.; Buchwald, S. L. Angew. Chem., Int. Ed. 2011,
50, 9120. (b) Liu, X.; Xiong, F.; Huang, X.; Xu, L.; Li, P.; Wu, X.
Angew. Chem., Int. Ed. 2013, 52, 6962. (c) Feng, C.; Loh, T.-P. Angew.
Chem., Int. Ed. 2013, 52, 12414. (d) Egami, H.; Shimizu, R.;
Kawamura, S.; Sodeoka, M. Angew. Chem., Int. Ed. 2013, 52, 4000.
(e) Chen, Z.; Bai, W.; Wang, S.; Yang, B.; Tu, Y.-Q.; Zhang, F. Angew.
Chem., Int. Ed. 2013, 52, 9781.
We gratefully acknowledge the National Natural Science
Foundation of China (21372114, 21172106, 21074054,
21290192, 21273102), the National Basic Research Program
of China (2010CB923303, 2011CB808600) and the Research
Fund for the Doctoral Program of Higher Education of China
(20120091110010) for their financial support.
(17) CCDC 958619 (14) and 953716 (32) contain the
supplementary crystallographic data for this paper.
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