Journal of labelled compounds and radiopharmaceuticals p. 745 - 754 (1995)
Update date:2022-08-05
Topics:
Joubert
Beney
Marsura
Luu-Duc
The condensation of ethyl acetoacetate-13C4 and ethyl bromoacetate-13C2 afforded, in seven steps, (1,2,3,4,5-13C5) 5-(diethylphosphono)-2-pentanone ethylene ketal 9. The reaction of this labelled compound with 7-[[(1,1-dimethylethyl)-dimethylsilyl]oxy]-1,6,6a,7,8, 9, 9a, 9b-octahydro-6a-methyl-[6aS-(6aa,7a,9aβ,9ba)] cyclopenta[f][1]benzopyran-3 (2H)-one 13 gave the benzindenone 14 which was converted to (1,2,3,4,10,19-13C6)testosterone 17 then, into (1,2,3,4,10-13C5)19-nortestosterone 18 by a reductive alkylation method.
View MoreAlpha(shijiazhuang) Chemical Co., Ltd
Contact:+86-311-85652680
Address:Shijiazhuang City ,Hebei Province China
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.
Contact:+86-0150-58101658
Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China
Shuanghe Bio-Technology Limited
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Zhengzhou Minzhong Pharmaceutical Co.,ltd
Contact:0086-371-65797115
Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China
Contact:0086 371 65711996
Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Doi:10.1021/jo701349c
(2008)Doi:10.1002/cmdc.201500439
(2016)Doi:10.1002/anie.200702726
(2007)Doi:10.1002/(SICI)1521-4184(19994)332:4<111::AID-ARDP111>3.0.CO;2-W
(1999)Doi:10.1246/cl.1983.1307
(1983)Doi:10.1021/om700586z
(2007)